Cargando…

Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells

Human T-cell leukemia virus type 1 (HTLV-1) is the etiological agent of adult T cell leukemia (ATL), which is an aggressive form of T-cell malignancy. HTLV-1 oncoproteins, Tax and HBZ, play crucial roles in the immortalization of T-cells and/or leukemogenesis by dysregulating the cellular functions...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takachi, Takayuki, Takahashi, Masahiko, Takahashi-Yoshita, Manami, Higuchi, Masaya, Obata, Miki, Mishima, Yukio, Okuda, Shujiro, Tanaka, Yuetsu, Matsuoka, Masao, Saitoh, Akihiko, Green, Patrick L, Fujii, Masahiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409891/ https://www.ncbi.nlm.nih.gov/pubmed/25613934 http://dx.doi.org/10.1111/cas.12618

Ejemplares similares

Distinct activities of HTLV-1 Tax1 from HTLV-2 Tax2 play key roles in pathogenesis
por: Fujii, Masahiro, et al.
Publicado: (2011)

PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell line
por: Tsubata, Chikako, et al.
Publicado: (2005)

Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax
por: Higuchi, Masaya, et al.
Publicado: (2014)

Promoter CpG methylation inhibits Krüppel-like factor 2 (KLF2)-Mediated repression of hTERT gene expression in human T-cells
por: Mizuguchi, Mariko, et al.
Publicado: (2021)

Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2
por: Shoji, Toshiyuki, et al.
Publicado: (2009)

Human T-cell leukemia virus type 2 Tax protein induces interleukin 2-independent growth in a T-cell line
por: Kondo, Rie, et al.
Publicado: (2006)

HTLV-1 Tax1 represses the proapoptotic protein Bim, which is crucial for T-cell transformation
por: Higuchi, Masaya, et al.
Publicado: (2011)

Inactivation of tumor suppressor Dlg1 augments transformation of a T-cell line induced by human T-cell leukemia virus type 1 Tax protein
por: Ishioka, Kojiro, et al.
Publicado: (2006)

Move or Die: the Fate of the Tax Oncoprotein of HTLV-1
por: Lodewick, Julie, et al.
Publicado: (2011)

Stress granules inhibit apoptosis by reducing ROS production, but this phenomenon is nullified by HTLV-1 Tax
por: Takahashi, Masahiko, et al.
Publicado: (2014)

Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein Tax
por: Wu, Xuefeng, et al.
Publicado: (2011)

Differential transforming activity of the retroviral Tax oncoproteins in human T lymphocytes
por: Ren, Tong, et al.
Publicado: (2013)

Akt activation by human T-cell leukemia virus tax oncoprotein
por: Cherian, Mathew, et al.
Publicado: (2015)

Biochemical analysis of the diverse functions of the HTLV-1-encoded oncoprotein Tax
por: Nyborg, Jennifer K, et al.
Publicado: (2014)

EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV-1 oncoprotein Tax and is downregulated in peripheral blood mononuclear cells of HTLV-1-infected individuals, irrespective of clinical statuses
por: Naito, Tadasuke, et al.
Publicado: (2019)

Antagonistic effects of HTLV-1 Tax oncoprotein on BRCA1 expression and function
por: Huleihel, Mahmoud, et al.
Publicado: (2014)

Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis
por: Higuchi, Masaya, et al.
Publicado: (2009)

bcl‐2 Gene Rearrangement Analysis in Japanese B Cell Lymphoma; Novel bcl‐2 Recombination with Immimoglobulin K Chain Gene
por: Osada, Hirotaka, et al.
Publicado: (1989)

Ubiquitination-dependent, proteasomal degradation of the retroviral oncoprotein Tax by niclosamide, an anti-helminthic molecule
por: Xiang, Di, et al.
Publicado: (2014)

The HTLV-1 oncoprotein Tax is modified by the ubiquitin related modifier 1 (Urm1)
por: Hleihel, Rita, et al.
Publicado: (2018)

Induction of Cell Death in Growing Human T-Cells and Cell Survival in Resting Cells in Response to the Human T-Cell Leukemia Virus Type 1 Tax
por: Mizuguchi, Mariko, et al.
Publicado: (2016)

Expression of the MOZ-TIF2 oncoprotein in mice represses senescence
por: Largeot, Anne, et al.
Publicado: (2016)

The Viral Oncoprotein Tax Sequesters DNA Damage Response Factors by Tethering MDC1 to Chromatin
por: Belgnaoui, S. Mehdi, et al.
Publicado: (2010)

The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape
por: Vandermeulen, Charlotte, et al.
Publicado: (2021)

Nuclear overexpression of bcl-2 oncoprotein during the progression of human stomach cancer.
por: Lee, S. S., et al.
Publicado: (1998)

Depletion of the oncoprotein Bcl-3 induces centrosome amplification and aneuploidy in cancer cells
por: Zamora, Ruben, et al.
Publicado: (2010)

Histopathological Evaluation and Analysis of Immunohistochemical Expression of Bcl-2 Oncoprotein in Colorectal Carcinoma
por: T Patil, Shilpa, et al.
Publicado: (2019)

The oncoprotein BCL6 enables solid tumor cells to evade genotoxic stress
por: Liu, Yanan, et al.
Publicado: (2022)

Human T-cell leukemia virus type-I Tax induces the expression of CD83 on T cells
por: Tanaka, Yuetsu, et al.
Publicado: (2015)

The SUMO-targeted ubiquitin ligase RNF4 regulates localization and function of the HTLV-1 oncoprotein Tax
por: Fryrear, Kimberly A, et al.
Publicado: (2011)

Examination of the interactions between the HTLV-1-encoded Tax oncoprotein and the cellular coactivators CBP/p300
por: Howard, Alisha D, et al.
Publicado: (2014)

Suppression of type I interferon production by human T-cell leukemia virus type 1 oncoprotein Tax
por: Jin, Dong-Yan, et al.
Publicado: (2014)

A transgenic Drosophila melanogaster model to study HTLV-I oncoprotein Tax-driven leukemogenesis in vivo
por: Shirinian, Margret, et al.
Publicado: (2015)

Hijacking of the O-GlcNAcZYME complex by the HTLV-1 Tax oncoprotein facilitates viral transcription
por: Groussaud, Damien, et al.
Publicado: (2017)

Post-translational modifications of the Tax oncoprotein of human T-cell leukemia virus control cytoplasmic and nuclear steps in Tax-mediated activation of the NF-κB pathway
por: Bex, Françoise, et al.
Publicado: (2009)

Alternative NF-κB Signaling Discriminates Induction of the Tumor Marker Fascin by the Viral Oncoproteins Tax-1 and Tax-2 of Human T-Cell Leukemia Viruses
por: Heym, Stefanie, et al.
Publicado: (2022)

SUV39H1 interacts with HTLV-1 Tax and abrogates Tax transactivation of HTLV-1 LTR
por: Kamoi, Koju, et al.
Publicado: (2006)

RGG-boxes of the EWS oncoprotein repress a range of transcriptional activation domains
por: Alex, Deepa, et al.
Publicado: (2005)

Physical and functional interaction between the HTLV-1 Tax oncoprotein and the cellular LIM domain protein FHL3
por: McCabe, Áine, et al.
Publicado: (2011)

Acetylation at lysine 346 controls the transforming activity of the HTLV-1 Tax oncoprotein in the Rat-1 fibroblast model
por: Lodewick, Julie, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_f5fcc35r3chojsa302g8rul91c