Sexually dimorphic gene expression emerges with embryonic genome activation and is dynamic throughout development

BACKGROUND: As sex determines mammalian development, understanding the nature and developmental dynamics of the sexually dimorphic transcriptome is important. To explore this, we generated 76 genome-wide RNA-seq profiles from mouse eight-cell embryos, late gestation and adult livers, together with 4...

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Detalles Bibliográficos
Autores principales: Lowe, Robert, Gemma, Carolina, Rakyan, Vardhman K, Holland, Michelle L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410000/
https://www.ncbi.nlm.nih.gov/pubmed/25888192
http://dx.doi.org/10.1186/s12864-015-1506-4

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