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Celastrol, a Chinese herbal compound, controls autoimmune inflammation by altering the balance of pathogenic and regulatory T cells in the target organ
Inflammation is an integral component of autoimmune arthritis. The balance of pathogenic T helper 17 (Th17) and protective T regulatory (Treg) cells can influence disease severity, and its resetting offers an attractive approach to control autoimmunity. We determined the frequency of Th17 and Treg i...
Autores principales: | Astry, Brian, Venkatesha, Shivaprasad H., Laurence, Arian, Christensen-Quick, Aaron, Garzinodemo, Alfredo, Frieman, Matthew B, O’Shea, John J., Moudgil, Kamal D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410084/ https://www.ncbi.nlm.nih.gov/pubmed/25660987 http://dx.doi.org/10.1016/j.clim.2015.01.011 |
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