Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis

Gut-associated inflammation plays a crucial role in the progression of colon cancer. Here, we identify a novel pathogen-host interaction that promotes gut inflammation and the development of colon cancer. We find that enteropathogenic bacteria-secreted particles (ET-BSPs) stimulate intestinal epithe...

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Detalles Bibliográficos
Autores principales: Deng, Zhongbin, Mu, Jingyao, Tseng, Michael, Wattenberg, Binks, Zhuang, Xiaoying, Egilmez, Nejat K, Wang, Qilong, Zhang, Lifeng, Norris, James, Guo, Haixun, Yan, Jun, Haribabu, Bodduluri, Miller, Donald, Zhang, Huang-Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410277/
https://www.ncbi.nlm.nih.gov/pubmed/25907800
http://dx.doi.org/10.1038/ncomms7956

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