Carbonic Anhydrase 9 Expression Increases with Vascular Endothelial Growth Factor–Targeted Therapy and Is Predictive of Outcome in Metastatic Clear Cell Renal Cancer

BACKGROUND: There is a lack of biomarkers to predict outcome with targeted therapy in metastatic clear cell renal cancer (mccRCC). This may be because dynamic molecular changes occur with therapy. OBJECTIVE: To explore if dynamic, targeted-therapy-driven molecular changes correlate with mccRCC outco...

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Detalles Bibliográficos
Autores principales: Stewart, Grant D., O’Mahony, Fiach C., Laird, Alexander, Rashid, Sukaina, Martin, Sarah A., Eory, Lel, Lubbock, Alexander L.R., Nanda, Jyoti, O’Donnell, Marie, Mackay, Alan, Mullen, Peter, McNeill, S. Alan, Riddick, Antony C.P., Aitchison, Michael, Berney, Daniel, Bex, Axel, Overton, Ian M., Harrison, David J., Powles, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
From Lab to Clinic
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410300/
https://www.ncbi.nlm.nih.gov/pubmed/24821582
http://dx.doi.org/10.1016/j.eururo.2014.04.007

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