Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks

BACKGROUND: A systems biology approach based on the assembly and interrogation of gene regulatory networks, or interactomes, was used to study neuroadaptation processes associated with the transition to alcohol dependence at the molecular level. RESULTS: Using a rat model of dependent and non-depend...

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Detalles Bibliográficos
Autores principales: Repunte-Canonigo, Vez, Shin, William, Vendruscolo, Leandro F, Lefebvre, Celine, van der Stap, Lena, Kawamura, Tomoya, Schlosburg, Joel E, Alvarez, Mariano, Koob, George F, Califano, Andrea, Sanna, Pietro Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410476/
https://www.ncbi.nlm.nih.gov/pubmed/25886852
http://dx.doi.org/10.1186/s13059-015-0593-5

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