Sterile alpha motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1)-facilitated HIV restriction in astrocytes is regulated by miRNA-181a

BACKGROUND: Although highly active antiretroviral therapy (HAART) has significantly reduced the morbidity and mortality in HIV patients, virus continues to reside in the central nervous system (CNS) reservoir. Hence, a complete eradication of virus remains a challenge. HIV productively infects micro...

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Detalles Bibliográficos
Autores principales: Pilakka-Kanthikeel, Sudheesh, Raymond, Andrea, Atluri, Venkata Subba Rao, Sagar, Vidya, Saxena, Shailendra K, Diaz, Patricia, Chevelon, Semithe, Concepcion, Michael, Nair, Madhavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410490/
https://www.ncbi.nlm.nih.gov/pubmed/25890101
http://dx.doi.org/10.1186/s12974-015-0285-9

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