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Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis

BACKGROUND: Therapeutic modalities effective in patients with progressive forms of multiple sclerosis (MS) are limited. In a murine model of progressive MS, the sustained disability during the chronic phase of experimental autoimmune encephalomyelitis (EAE) correlated with elevated expression of int...

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Detalles Bibliográficos
Autores principales:	Savarin, Carine, Hinton, David R, Valentin-Torres, Alice, Chen, Zhihong, Trapp, Bruce D, Bergmann, Cornelia C, Stohlman, Stephen A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410573/ https://www.ncbi.nlm.nih.gov/pubmed/25896970 http://dx.doi.org/10.1186/s12974-015-0293-9

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