Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells

BACKGROUND: An increase in circulating platelets, or thrombocytosis, is recognized as an independent risk factor of bad prognosis and metastasis in patients with ovarian cancer; however the complex role of platelets in tumor progression has not been fully elucidated. Platelet activation has been ass...

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Detalles Bibliográficos
Autores principales: Orellana, Renan, Kato, Sumie, Erices, Rafaela, Bravo, María Loreto, Gonzalez, Pamela, Oliva, Bárbara, Cubillos, Sofía, Valdivia, Andrés, Ibañez, Carolina, Brañes, Jorge, Barriga, María Isabel, Bravo, Erasmo, Alonso, Catalina, Bustamente, Eva, Castellon, Enrique, Hidalgo, Patricia, Trigo, Cesar, Panes, Olga, Pereira, Jaime, Mezzano, Diego, Cuello, Mauricio A, Owen, Gareth I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410584/
https://www.ncbi.nlm.nih.gov/pubmed/25886038
http://dx.doi.org/10.1186/s12885-015-1304-z

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