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The rare BRAF VK600-601E mutation as a possible indicator of poor prognosis in rectal carcinoma – a report of a case
BACKGROUND: The BRAF V600E mutation is reportedly associated with inferior survival among colon cancer patients. Here we report a patient with rectal cancer who carried the novel BRAF mutation VK600–601E, which has analogous molecular functions to those of the conventional BRAF mutation V600E, and m...
Autores principales: | Mori, Yoshiko, Nagasaka, Takeshi, Mishima, Hideyuki, Umeda, Yuzo, Inada, Ryo, Kishimoto, Hiroyuki, Goel, Ajay, Fujiwara, Toshiyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410594/ https://www.ncbi.nlm.nih.gov/pubmed/25636897 http://dx.doi.org/10.1186/s12881-015-0144-7 |
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