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Notch signaling respecifies the hemangioblast to a cardiac fate

To efficiently generate cardiomyocytes from embryonic stem (ES) cells in culture it is essential to identify key regulators of the cardiac lineage and to develop methods to control them. Using a tet-inducible ES cell line to enforce expression of a constitutively activated form of the Notch 4 recept...

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Detalles Bibliográficos
Autores principales: Chen, Vincent C., Stull, Robert, Joo, Daniel, Cheng, Xin, Keller, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410743/
https://www.ncbi.nlm.nih.gov/pubmed/18820686
http://dx.doi.org/10.1038/nbt.1497

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