Antimalarial NADPH-Consuming Redox-Cyclers As Superior Glucose-6-Phosphate Dehydrogenase Deficiency Copycats

Aims: Early phagocytosis of glucose-6-phosphate dehydrogenase (G6PD)-deficient erythrocytes parasitized by Plasmodium falciparum were shown to protect G6PD-deficient populations from severe malaria. Here, we investigated the mechanism of a novel antimalarial series, namely 3-[substituted-benzyl]-men...

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Detalles Bibliográficos
Autores principales: Bielitza, Max, Belorgey, Didier, Ehrhardt, Katharina, Johann, Laure, Lanfranchi, Don Antoine, Gallo, Valentina, Schwarzer, Evelin, Mohring, Franziska, Jortzik, Esther, Williams, David L., Becker, Katja, Arese, Paolo, Elhabiri, Mourad, Davioud-Charvet, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Original Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410756/
https://www.ncbi.nlm.nih.gov/pubmed/25714942
http://dx.doi.org/10.1089/ars.2014.6047

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