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Cytoplasmic Dynein Transports Cargos via Load-Sharing between the Heads
Cytoplasmic dynein is a motor protein that walks along microtubules (MTs) and performs mechanical work to power a variety of cellular processes. It remains unclear how a dynein dimer is able to transport cargos against load without coordinating the stepping cycles of its two heads. Here, by using a...
Autores principales: | Belyy, Vladislav, Hendel, Nathan L., Chien, Alexander, Yildiz, Ahmet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410804/ https://www.ncbi.nlm.nih.gov/pubmed/25424027 http://dx.doi.org/10.1038/ncomms6544 |
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