The Structure of the PanD/PanZ Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A

Coenzyme A (CoA) is an ubiquitous and essential cofactor, synthesized from the precursor pantothenate. Vitamin biosynthetic pathways are normally tightly regulated, including the pathway from pantothenate to CoA. However, no regulation of pantothenate biosynthesis has been identified. We have recent...

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Detalles Bibliográficos
Autores principales: Monteiro, Diana C.F., Patel, Vijay, Bartlett, Christopher P., Nozaki, Shingo, Grant, Thomas D., Gowdy, James A., Thompson, Gary S., Kalverda, Arnout P., Snell, Edward H., Niki, Hironori, Pearson, Arwen R., Webb, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410942/
https://www.ncbi.nlm.nih.gov/pubmed/25910242
http://dx.doi.org/10.1016/j.chembiol.2015.03.017

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