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Pachymic Acid Inhibits Growth and Induces Apoptosis of Pancreatic Cancer In Vitro and In Vivo by Targeting ER Stress

Pachymic acid (PA) is a purified triterpene extracted from medicinal fungus Poria cocos. In this paper, we investigated the anticancer effect of PA on human chemotherapy resistant pancreatic cancer. PA triggered apoptosis in gemcitabine-resistant pancreatic cancer cells PANC-1 and MIA PaCa-2. Compar...

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Detalles Bibliográficos
Autores principales:	Cheng, Shujie, Swanson, Kristen, Eliaz, Isaac, McClintick, Jeanette N., Sandusky, George E., Sliva, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411097/ https://www.ncbi.nlm.nih.gov/pubmed/25915041 http://dx.doi.org/10.1371/journal.pone.0122270

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