WDR12, a Member of Nucleolar PeBoW-Complex, Is Up-Regulated in Failing Hearts and Causes Deterioration of Cardiac Function

AIMS: In a recent genome-wide association study, WD-repeat domain 12 (WDR12) was associated with early-onset myocardial infarction (MI). However, the function of WDR12 in the heart is unknown. METHODS AND RESULTS: We characterized cardiac expression of WDR12, used adenovirus-mediated WDR12 gene deli...

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Detalles Bibliográficos
Autores principales: Moilanen, Anne-Mari, Rysä, Jaana, Kaikkonen, Leena, Karvonen, Teemu, Mustonen, Erja, Serpi, Raisa, Szabó, Zoltán, Tenhunen, Olli, Bagyura, Zsolt, Näpänkangas, Juha, Ohukainen, Pauli, Tavi, Pasi, Kerkelä, Risto, Leósdóttir, Margrét, Wahlstrand, Björn, Hedner, Thomas, Melander, Olle, Ruskoaho, Heikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411154/
https://www.ncbi.nlm.nih.gov/pubmed/25915632
http://dx.doi.org/10.1371/journal.pone.0124907

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