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Toll-Interacting Protein Suppresses HIV-1 Long-Terminal-Repeat-Driven Gene Expression and Silences the Post-Integrational Transcription of Viral Proviral DNA

Toll-interacting protein (Tollip) is a host adaptor protein for negatively regulating Toll-like receptor 2-, 4-, and IL-1R (interleukin-1 receptor)-mediated signaling. We found that Tollip expression could be induced in MDDCs (monocyte-derived dendritic cells) by HIV-1 particles and recombinant gp12...

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Detalles Bibliográficos
Autores principales: Yang, Fu-Chun, Kuang, Wen-Dong, Li, Chuan, Sun, Wei-Wei, Qu, Di, Wang, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411168/
https://www.ncbi.nlm.nih.gov/pubmed/25915421
http://dx.doi.org/10.1371/journal.pone.0125563