Mechanism for phosphoinositide selectivity and activation of TRPV1 ion channels

Although PI(4,5)P(2) is believed to play an essential role in regulating the activity of numerous ion channels and transporters, the mechanisms by which it does so are unknown. Here, we used the ability of the TRPV1 ion channel to discriminate between PI(4,5)P(2) and PI(4)P to localize the region of...

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Detalles Bibliográficos
Autores principales: Ufret-Vincenty, Carmen A., Klein, Rebecca M., Collins, Marcus D., Rosasco, Mario G., Martinez, Gilbert Q., Gordon, Sharona E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411251/
https://www.ncbi.nlm.nih.gov/pubmed/25918361
http://dx.doi.org/10.1085/jgp.201511354

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