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Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear

The maintenance of sensory hair cell stereocilia is critical for lifelong hearing; however, mechanisms of structural homeostasis remain poorly understood. Conflicting models propose that stereocilia F-actin cores are either continually renewed every 24–48 h via a treadmill or are stable, exceptional...

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Detalles Bibliográficos
Autores principales: Drummond, Meghan C., Barzik, Melanie, Bird, Jonathan E., Zhang, Duan-Sun, Lechene, Claude P., Corey, David P., Cunningham, Lisa L., Friedman, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411292/
https://www.ncbi.nlm.nih.gov/pubmed/25898120
http://dx.doi.org/10.1038/ncomms7873

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