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Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear
The maintenance of sensory hair cell stereocilia is critical for lifelong hearing; however, mechanisms of structural homeostasis remain poorly understood. Conflicting models propose that stereocilia F-actin cores are either continually renewed every 24–48 h via a treadmill or are stable, exceptional...
Autores principales: | Drummond, Meghan C., Barzik, Melanie, Bird, Jonathan E., Zhang, Duan-Sun, Lechene, Claude P., Corey, David P., Cunningham, Lisa L., Friedman, Thomas B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411292/ https://www.ncbi.nlm.nih.gov/pubmed/25898120 http://dx.doi.org/10.1038/ncomms7873 |
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