APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages

The extent, regulation and enzymatic basis of RNA editing by cytidine deamination are incompletely understood. Here we show that transcripts of hundreds of genes undergo site-specific C>U RNA editing in macrophages during M1 polarization and in monocytes in response to hypoxia and interferons. Th...

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Detalles Bibliográficos
Autores principales: Sharma, Shraddha, Patnaik, Santosh K., Thomas Taggart, R., Kannisto, Eric D., Enriquez, Sally M., Gollnick, Paul, Baysal, Bora E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411297/
https://www.ncbi.nlm.nih.gov/pubmed/25898173
http://dx.doi.org/10.1038/ncomms7881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411297/
https://www.ncbi.nlm.nih.gov/pubmed/25898173
http://dx.doi.org/10.1038/ncomms7881

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