The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract

Vimentin is an intermediate filament protein normally expressed in cells of mesenchymal origin, e.g. myofibroblasts, chondrocytes, macrophages, and endothelial cells. The expression of vimentin, which has been thought of as the main mesenchymal marker, is also detected in tumour tissue. In tumours o...

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Detalles Bibliográficos
Autores principales: Brzozowa, Marlena, Wyrobiec, Grzegorz, Kołodziej, Izabela, Sitarski, Mateusz, Matysiak, Natalia, Reichman-Warmusz, Edyta, Żaba, Małgorzata, Wojnicz, Romuald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2015
Materias:
Review Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411408/
https://www.ncbi.nlm.nih.gov/pubmed/25960808
http://dx.doi.org/10.5114/pg.2014.47502
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author Brzozowa, Marlena
Wyrobiec, Grzegorz
Kołodziej, Izabela
Sitarski, Mateusz
Matysiak, Natalia
Reichman-Warmusz, Edyta
Żaba, Małgorzata
Wojnicz, Romuald
author_facet Brzozowa, Marlena
Wyrobiec, Grzegorz
Kołodziej, Izabela
Sitarski, Mateusz
Matysiak, Natalia
Reichman-Warmusz, Edyta
Żaba, Małgorzata
Wojnicz, Romuald
author_sort Brzozowa, Marlena
collection PubMed
description Vimentin is an intermediate filament protein normally expressed in cells of mesenchymal origin, e.g. myofibroblasts, chondrocytes, macrophages, and endothelial cells. The expression of vimentin, which has been thought of as the main mesenchymal marker, is also detected in tumour tissue. In tumours of the gastrointestinal tract vimentin expression is usually correlated with advanced stage of tumour, lymph node metastasis, and patient survival.
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spelling pubmed-44114082015-05-08 The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract Brzozowa, Marlena Wyrobiec, Grzegorz Kołodziej, Izabela Sitarski, Mateusz Matysiak, Natalia Reichman-Warmusz, Edyta Żaba, Małgorzata Wojnicz, Romuald Prz Gastroenterol Review Paper Vimentin is an intermediate filament protein normally expressed in cells of mesenchymal origin, e.g. myofibroblasts, chondrocytes, macrophages, and endothelial cells. The expression of vimentin, which has been thought of as the main mesenchymal marker, is also detected in tumour tissue. In tumours of the gastrointestinal tract vimentin expression is usually correlated with advanced stage of tumour, lymph node metastasis, and patient survival. Termedia Publishing House 2015-01-14 2015 /pmc/articles/PMC4411408/ /pubmed/25960808 http://dx.doi.org/10.5114/pg.2014.47502 Text en Copyright © 2015 Termedia http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Paper
Brzozowa, Marlena
Wyrobiec, Grzegorz
Kołodziej, Izabela
Sitarski, Mateusz
Matysiak, Natalia
Reichman-Warmusz, Edyta
Żaba, Małgorzata
Wojnicz, Romuald
The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract
title The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract
title_full The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract
title_fullStr The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract
title_full_unstemmed The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract
title_short The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract
title_sort aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract
topic Review Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411408/
https://www.ncbi.nlm.nih.gov/pubmed/25960808
http://dx.doi.org/10.5114/pg.2014.47502
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