Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen

58-year-old man presented with headache, nausea, vomiting, and gait disturbance. Brain MRI showed meningeal enhancement and herniation. Serum Cryptococcus antigen was positive but spinal fluid antigen and cultures were negative. A cerebellar biopsy revealed nonencapsulated Cryptococcus. He completed...

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Detalles Bibliográficos
Autores principales: Garcia-Santibanez, Rocio C., Gill, Veenu, Yancovitz, Stanley, Pyburn, DeWitt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411463/
https://www.ncbi.nlm.nih.gov/pubmed/25954558
http://dx.doi.org/10.1155/2015/857539
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author Garcia-Santibanez, Rocio C.
Gill, Veenu
Yancovitz, Stanley
Pyburn, DeWitt
author_facet Garcia-Santibanez, Rocio C.
Gill, Veenu
Yancovitz, Stanley
Pyburn, DeWitt
author_sort Garcia-Santibanez, Rocio C.
collection PubMed
description 58-year-old man presented with headache, nausea, vomiting, and gait disturbance. Brain MRI showed meningeal enhancement and herniation. Serum Cryptococcus antigen was positive but spinal fluid antigen and cultures were negative. A cerebellar biopsy revealed nonencapsulated Cryptococcus. He completed antifungal therapy. Serum Cryptococcus antigen titer decreased. He had a full neurological recovery.
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spelling pubmed-44114632015-05-07 Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen Garcia-Santibanez, Rocio C. Gill, Veenu Yancovitz, Stanley Pyburn, DeWitt Case Rep Infect Dis Case Report 58-year-old man presented with headache, nausea, vomiting, and gait disturbance. Brain MRI showed meningeal enhancement and herniation. Serum Cryptococcus antigen was positive but spinal fluid antigen and cultures were negative. A cerebellar biopsy revealed nonencapsulated Cryptococcus. He completed antifungal therapy. Serum Cryptococcus antigen titer decreased. He had a full neurological recovery. Hindawi Publishing Corporation 2015 2015-04-14 /pmc/articles/PMC4411463/ /pubmed/25954558 http://dx.doi.org/10.1155/2015/857539 Text en Copyright © 2015 Rocio C. Garcia-Santibanez et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Garcia-Santibanez, Rocio C.
Gill, Veenu
Yancovitz, Stanley
Pyburn, DeWitt
Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen
title Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen
title_full Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen
title_fullStr Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen
title_full_unstemmed Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen
title_short Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen
title_sort neuroinvasive cryptococcosis in an immunocompetent patient with a negative spinal fluid cryptococcus antigen
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411463/
https://www.ncbi.nlm.nih.gov/pubmed/25954558
http://dx.doi.org/10.1155/2015/857539
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AT yancovitzstanley neuroinvasivecryptococcosisinanimmunocompetentpatientwithanegativespinalfluidcryptococcusantigen
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