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Axial strain enhances osteotomy repair with a concomitant increase in connexin43 expression

The mechanical environment is known to influence fracture healing. We speculated that connexin43 (Cx43) gap junctions, which impact skeletal homeostasis, fracture healing and the osteogenic response to mechanical load, may play a role in mediating the response of the healing bone to mechanical strai...

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Detalles Bibliográficos
Autores principales: Gupta, Rishi R, Kim, Hyunchul, Chan, Yu-Kwan, Hebert, Carla, Gitajn, Leah, Yoo, David J, O'Toole, Robert V, Hsieh, Adam H, Stains, Joseph P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411567/
https://www.ncbi.nlm.nih.gov/pubmed/26273538
http://dx.doi.org/10.1038/boneres.2015.7