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Amiodarone-Induced Multiorgan Toxicity with Ocular Findings on Confocal Microscopy

Amiodarone is an antiarrhythmic medication that can adversely effect various organs including lungs, thyroid gland, liver, eyes, skin, and nerves. The risk of adverse effects increases with high doses and prolonged use. We report a 54-year-old female who presented with multiorgan toxicity after 8 mo...

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Detalles Bibliográficos
Autores principales: Turk, Ugur, Turk, Bengu Gerceker, Yılmaz, Suzan Guven, Tuncer, Esref, Alioğlu, Emin, Dereli, Tugrul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411629/
https://www.ncbi.nlm.nih.gov/pubmed/25949090
http://dx.doi.org/10.4103/0974-9233.154411
Descripción
Sumario:Amiodarone is an antiarrhythmic medication that can adversely effect various organs including lungs, thyroid gland, liver, eyes, skin, and nerves. The risk of adverse effects increases with high doses and prolonged use. We report a 54-year-old female who presented with multiorgan toxicity after 8 months of low dose (200 mg/day) amiodarone treatment. The findings of confocal microscopy due to amiodarone-induced keratopathy are described. Amiodarone may cause multiorgan toxicity even at lower doses and for shorter treatment periods.