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Humanized-V(H)H Transbodies that Inhibit HCV Protease and Replication

There is a need for safe and broadly effective anti-HCV agents that can cope with genetic multiplicity and mutations of the virus. In this study, humanized-camel V(H)Hs to genotype 3a HCV serine protease were produced and were linked molecularly to a cell penetrating peptide, penetratin (PEN). Human...

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Detalles Bibliográficos
Autores principales:	Jittavisutthikul, Surasak, Thanongsaksrikul, Jeeraphong, Thueng-in, Kanyarat, Chulanetra, Monrat, Srimanote, Potjanee, Seesuay, Watee, Malik, Aijaz Ahmad, Chaicumpa, Wanpen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411689/ https://www.ncbi.nlm.nih.gov/pubmed/25903832 http://dx.doi.org/10.3390/v7042030

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