Rheumatoid arthritis response to treatment across IgG1 allotype – anti-TNF incompatibility: a case-only study

INTRODUCTION: We have hypothesized that incompatibility between the G1m genotype of the patient and the G1m1 and G1m17 allotypes carried by infliximab (INX) and adalimumab (ADM) could decrease the efficacy of these anti-tumor necrosis factor (anti-TNF) antibodies in the treatment of rheumatoid arthr...

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Detalles Bibliográficos
Autores principales: Montes, Ariana, Perez-Pampin, Eva, Navarro-Sarabia, Federico, Moreira, Virginia, de la Serna, Arturo Rodríguez, Magallares, Berta, Vasilopoulos, Yiannis, Sarafidou, Theologia, Fernández-Nebro, Antonio, Ordóñez, María del Carmen, Narváez, Javier, Cañete, Juan D, Marquez, Ana, Pascual-Salcedo, Dora, Joven, Beatriz, Carreira, Patricia, Moreno-Ramos, Manuel J, Caliz, Rafael, Ferrer, Miguel Angel, Garcia-Portales, Rosa, Blanco, Francisco J, Magro, Cesar, Raya, Enrique, Valor, Lara, Alegre-Sancho, Juan J, Balsa, Alejandro, Martin, Javier, Plant, Darren, Isaacs, John, Morgan, Ann W, Barton, Anne, Wilson, Anthony G, Gómez-Reino, Juan J, Gonzalez, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411723/
https://www.ncbi.nlm.nih.gov/pubmed/25885039
http://dx.doi.org/10.1186/s13075-015-0571-z

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