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Left ventricular diastolic function associated with common genetic variation in ATP12A in a general population
BACKGROUND: Left ventricular (LV) function depends on the activity of transmembrane electrolyte transporters. Failing human myocardium has lower Na(+)/K(+) ATPase expression and higher intracellular sodium concentrations. The ATP12A gene encodes a catalytic subunit of an ATPase that can function as...
Autores principales: | Knez, Judita, Salvi, Erika, Tikhonoff, Valérie, Stolarz-Skrzypek, Katarzyna, Ryabikov, Andrew, Thijs, Lutgarde, Braga, Daniele, Kloch-Badelek, Malgorzata, Malyutina, Sofia, Casiglia, Edoardo, Czarnecka, Danuta, Kawecka-Jaszcz, Kalina, Cusi, Daniele, Nawrot, Tim, Staessen, Jan A, Kuznetsova, Tatiana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411923/ https://www.ncbi.nlm.nih.gov/pubmed/25366262 http://dx.doi.org/10.1186/s12881-014-0121-6 |
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