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Proteomic analysis of media from lung cancer cells reveals role of 14-3-3 proteins in cachexia

Aims: At the time of diagnosis, 60% of lung cancer patients present with cachexia, a severe wasting syndrome that increases morbidity and mortality. Tumors secrete multiple factors that contribute to cachectic muscle wasting, and not all of these factors have been identified. We used Orbitrap electr...

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Detalles Bibliográficos
Autores principales: McLean, Julie B., Moylan, Jennifer S., Horrell, Erin M. W., Andrade, Francisco H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411971/
https://www.ncbi.nlm.nih.gov/pubmed/25972815
http://dx.doi.org/10.3389/fphys.2015.00136