Reversal of Jaundice in Two Patients with Inoperable Cholangiocarcinoma Treated with Cisplatin and Gemcitabine Combination

Two patients are presented with severe jaundice, due to inoperable cholangiocarcinoma. The chemotherapeutic approach in patients with severe jaundice is discussed. Many schedules of chemotherapy were developed in this tumor type with normal serum bilirubin. We report here the first successful use of...

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Autores principales: Criel, Maarten, Geurs, Filip, Ponette, Siegfried, Bulte, Katrien, Ponette, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412096/
https://www.ncbi.nlm.nih.gov/pubmed/25954551
http://dx.doi.org/10.1155/2012/138381
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author Criel, Maarten
Geurs, Filip
Ponette, Siegfried
Bulte, Katrien
Ponette, Johan
author_facet Criel, Maarten
Geurs, Filip
Ponette, Siegfried
Bulte, Katrien
Ponette, Johan
author_sort Criel, Maarten
collection PubMed
description Two patients are presented with severe jaundice, due to inoperable cholangiocarcinoma. The chemotherapeutic approach in patients with severe jaundice is discussed. Many schedules of chemotherapy were developed in this tumor type with normal serum bilirubin. We report here the first successful use of cisplatin and gemcitabine combination chemotherapy in these patients. Tolerability was good and liver function tests gradually improved.
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spelling pubmed-44120962015-05-07 Reversal of Jaundice in Two Patients with Inoperable Cholangiocarcinoma Treated with Cisplatin and Gemcitabine Combination Criel, Maarten Geurs, Filip Ponette, Siegfried Bulte, Katrien Ponette, Johan Case Reports Hepatol Case Report Two patients are presented with severe jaundice, due to inoperable cholangiocarcinoma. The chemotherapeutic approach in patients with severe jaundice is discussed. Many schedules of chemotherapy were developed in this tumor type with normal serum bilirubin. We report here the first successful use of cisplatin and gemcitabine combination chemotherapy in these patients. Tolerability was good and liver function tests gradually improved. Hindawi Publishing Corporation 2012 2012-03-20 /pmc/articles/PMC4412096/ /pubmed/25954551 http://dx.doi.org/10.1155/2012/138381 Text en Copyright © 2012 Maarten Criel et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Criel, Maarten
Geurs, Filip
Ponette, Siegfried
Bulte, Katrien
Ponette, Johan
Reversal of Jaundice in Two Patients with Inoperable Cholangiocarcinoma Treated with Cisplatin and Gemcitabine Combination
title Reversal of Jaundice in Two Patients with Inoperable Cholangiocarcinoma Treated with Cisplatin and Gemcitabine Combination
title_full Reversal of Jaundice in Two Patients with Inoperable Cholangiocarcinoma Treated with Cisplatin and Gemcitabine Combination
title_fullStr Reversal of Jaundice in Two Patients with Inoperable Cholangiocarcinoma Treated with Cisplatin and Gemcitabine Combination
title_full_unstemmed Reversal of Jaundice in Two Patients with Inoperable Cholangiocarcinoma Treated with Cisplatin and Gemcitabine Combination
title_short Reversal of Jaundice in Two Patients with Inoperable Cholangiocarcinoma Treated with Cisplatin and Gemcitabine Combination
title_sort reversal of jaundice in two patients with inoperable cholangiocarcinoma treated with cisplatin and gemcitabine combination
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412096/
https://www.ncbi.nlm.nih.gov/pubmed/25954551
http://dx.doi.org/10.1155/2012/138381
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AT ponettesiegfried reversalofjaundiceintwopatientswithinoperablecholangiocarcinomatreatedwithcisplatinandgemcitabinecombination
AT bultekatrien reversalofjaundiceintwopatientswithinoperablecholangiocarcinomatreatedwithcisplatinandgemcitabinecombination
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