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R-loops and initiation of DNA replication in human cells: a missing link?

The unanticipated widespread occurrence of stable hybrid DNA/RNA structures (R-loops) in human cells and the increasing evidence of their involvement in several human malignancies have invigorated the research on R-loop biology in recent years. Here we propose that physiological R-loop formation at...

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Detalles Bibliográficos
Autores principales:	Lombraña, Rodrigo, Almeida, Ricardo, Álvarez, Alba, Gómez, María
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412123/ https://www.ncbi.nlm.nih.gov/pubmed/25972891 http://dx.doi.org/10.3389/fgene.2015.00158

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