Mutational analysis of BRCA1/2 in a group of 134 consecutive ovarian cancer patients. Novel and recurrent BRCA1/2 alterations detected by next generation sequencing

The importance of proper mutational analysis of BRCA1/2 in individuals at risk for hereditary breast and ovarian cancer syndrome is widely accepted. Standard genetic screening includes targeted analysis of recurrent, population-specific mutations. The purpose of the study was to establish the freque...

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Detalles Bibliográficos
Autores principales: Ratajska, Magdalena, Krygier, Magdalena, Stukan, Maciej, Kuźniacka, Alina, Koczkowska, Magdalena, Dudziak, Mirosław, Śniadecki, Marcin, Dębniak, Jarosław, Wydra, Dariusz, Brozek, Izabela, Biernat, Wojciech, Borg, Ake, Limon, Janusz, Wasąg, Bartosz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Human Genetics • Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412280/
https://www.ncbi.nlm.nih.gov/pubmed/25366421
http://dx.doi.org/10.1007/s13353-014-0254-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412280/
https://www.ncbi.nlm.nih.gov/pubmed/25366421
http://dx.doi.org/10.1007/s13353-014-0254-5

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