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A Specific A/T Polymorphism in Western Tyrosine Phosphorylation B-Motifs Regulates Helicobacter pylori CagA Epithelial Cell Interactions

Helicobacter pylori persistently colonizes the human stomach, with mixed roles in human health. The CagA protein, a key host-interaction factor, is translocated by a type IV secretion system into host epithelial cells, where its EPIYA tyrosine phosphorylation motifs (TPMs) are recognized by host cel...

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Detalles Bibliográficos
Autores principales: Zhang, Xue-Song, Tegtmeyer, Nicole, Traube, Leah, Jindal, Shawn, Perez-Perez, Guillermo, Sticht, Heinrich, Backert, Steffen, Blaser, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412286/
https://www.ncbi.nlm.nih.gov/pubmed/25646814
http://dx.doi.org/10.1371/journal.ppat.1004621

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