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The Genetic Architecture of the Genome-Wide Transcriptional Response to ER Stress in the Mouse
Endoplasmic reticulum (ER) stress occurs when misfolded proteins accumulate in the ER. The cellular response to ER stress involves complex transcriptional and translational changes, important to the survival of the cell. ER stress is a primary cause and a modifier of many human diseases. A first ste...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412289/ https://www.ncbi.nlm.nih.gov/pubmed/25651210 http://dx.doi.org/10.1371/journal.pgen.1004924 |