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The Genetic Architecture of the Genome-Wide Transcriptional Response to ER Stress in the Mouse

Endoplasmic reticulum (ER) stress occurs when misfolded proteins accumulate in the ER. The cellular response to ER stress involves complex transcriptional and translational changes, important to the survival of the cell. ER stress is a primary cause and a modifier of many human diseases. A first ste...

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Detalles Bibliográficos
Autores principales: Chow, Clement Y, Wang, Xu, Riccardi, David, Wolfner, Mariana F., Clark, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412289/
https://www.ncbi.nlm.nih.gov/pubmed/25651210
http://dx.doi.org/10.1371/journal.pgen.1004924