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Activation of autophagy protects against cholestasis-induced hepatic injury

BACKGROUND: Cholestasis is characterized by an abnormal accumulation of bile acids and causes hepatocellular injury. Recent studies show that autophagy is involved in the pathophysiology of many liver diseases. The potential role of autophagy in preventing cholestatic hepatotoxicity, however, has ra...

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Detalles Bibliográficos
Autores principales: Gao, Lu, Lv, Gang, Guo, Xianling, Jing, Yingying, Han, Zhipeng, Zhang, Shanshan, Sun, Kai, Li, Rong, Yang, Yang, Wei, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412295/
https://www.ncbi.nlm.nih.gov/pubmed/25922659
http://dx.doi.org/10.1186/2045-3701-4-47