Cargando…
In vivo PET imaging of beta-amyloid deposition in mouse models of Alzheimer's disease with a high specific activity PET imaging agent [(18)F]flutemetamol
BACKGROUND: The purpose of the study was to evaluate the applicability of (18)F-labelled amyloid imaging positron emission tomography (PET) agent [(18)F]flutemetamol to detect changes in brain beta-amyloid (Aβ) deposition in vivo in APP23, Tg2576 and APPswe-PS1dE9 mouse models of Alzheimer's di...
Autores principales: | Snellman, Anniina, Rokka, Johanna, López-Picón, Francisco R, Eskola, Olli, Salmona, Mario, Forloni, Gianluigi, Scheinin, Mika, Solin, Olof, Rinne, Juha O, Haaparanta-Solin, Merja |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412375/ https://www.ncbi.nlm.nih.gov/pubmed/25977876 http://dx.doi.org/10.1186/s13550-014-0037-3 |
Ejemplares similares
-
Effect of genotype and age on cerebral [(18)F]FDG uptake varies between transgenic APP(Swe)-PS1(dE9) and Tg2576 mouse models of Alzheimer’s disease
por: Snellman, Anniina, et al.
Publicado: (2019) -
ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer’s disease with a bispecific, brain-penetrating fusion protein
por: Bonvicini, Gillian, et al.
Publicado: (2022) -
[(18)F]SPA-RQ/PET Study of NK1 receptors in the Whole Body of Guinea Pig and Rat
por: Grönroos, Tove J., et al.
Publicado: (2019) -
Monoacylglycerol lipase inhibitor JZL184 reduces neuroinflammatory response in APdE9 mice and in adult mouse glial cells
por: Pihlaja, Rea, et al.
Publicado: (2015) -
[(18)F]CFT synthesis and binding to monoamine transporters in rats
por: Forsback, Sarita, et al.
Publicado: (2012)