Intra-adrenal murine TH-MYCN neuroblastoma tumors grow more aggressive and exhibit a distinct tumor microenvironment relative to their subcutaneous equivalents

In around half of the patients with neuroblastoma (NBL), the primary tumor is located in one of the adrenal glands. We have previously reported on a transplantable TH-MYCN model of subcutaneous (SC) growing NBL in C57Bl/6 mice for immunological studies. In this report, we describe an orthotopic TH-M...

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Detalles Bibliográficos
Autores principales: Kroesen, Michiel, Brok, Ingrid C., Reijnen, Daphne, van Hout-Kuijer, Maaike A., Zeelenberg, Ingrid S., Den Brok, Martijn H., Hoogerbrugge, Peter M., Adema, Gosse J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412512/
https://www.ncbi.nlm.nih.gov/pubmed/25687736
http://dx.doi.org/10.1007/s00262-015-1663-y

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