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AMP-18 Targets p21 to Maintain Epithelial Homeostasis

Dysregulated homeostasis of epithelial cells resulting in disruption of mucosal barrier function is an important pathogenic mechanism in inflammatory bowel diseases (IBD). We have characterized a novel gastric protein, Antrum Mucosal Protein (AMP)-18, that has pleiotropic properties; it is mitogenic...

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Detalles Bibliográficos
Autores principales: Chen, Peili, Li, Yan Chun, Toback, F. Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412538/
https://www.ncbi.nlm.nih.gov/pubmed/25919700
http://dx.doi.org/10.1371/journal.pone.0125490