Identifying Human Genome-Wide CNV, LOH and UPD by Targeted Sequencing of Selected Regions

Copy-number variations (CNV), loss of heterozygosity (LOH), and uniparental disomy (UPD) are large genomic aberrations leading to many common inherited diseases, cancers, and other complex diseases. An integrated tool to identify these aberrations is essential in understanding diseases and in design...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Li, Wei, Xia, Yingying, Wang, Chongzhi, Tang, Y. Tom, Guo, Wenying, Li, Jinliang, Zhao, Xia, Sun, Yepeng, Hu, Juan, Zhen, Hefu, Zhang, Xiandong, Chen, Chao, Shi, Yujian, Li, Lin, Cao, Hongzhi, Du, Hongli, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412667/
https://www.ncbi.nlm.nih.gov/pubmed/25919136
http://dx.doi.org/10.1371/journal.pone.0123081

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