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Impact of Acute Malaria on Pre-Existing Antibodies to Viral and Vaccine Antigens in Mice and Humans

Vaccine-induced immunity depends on long-lived plasma cells (LLPCs) that maintain antibody levels. A recent mouse study showed that Plasmodium chaubaudi infection reduced pre-existing influenza-specific antibodies—raising concerns that malaria may compromise pre-existing vaccine responses. We extend...

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Detalles Bibliográficos
Autores principales:	Banga, Simran, Coursen, Jill D., Portugal, Silvia, Tran, Tuan M., Hancox, Lisa, Ongoiba, Aissata, Traore, Boubacar, Doumbo, Ogobara K., Huang, Chiung-Yu, Harty, John T., Crompton, Peter D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412709/ https://www.ncbi.nlm.nih.gov/pubmed/25919588 http://dx.doi.org/10.1371/journal.pone.0125090

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