A (14)C-leucine absorption, distribution, metabolism and excretion (ADME) study in adult Sprague–Dawley rat reveals β-hydroxy-β-methylbutyrate as a metabolite

Leucine is an essential branched-chain amino acid that acts as a substrate for protein synthesis and as a signaling molecule. Leucine not incorporated into muscle protein is ultimately oxidized through intermediates such as β-hydroxy-β-methylbutyrate (HMB) which itself is reported to enhance muscle...

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Detalles Bibliográficos
Autores principales: Lee, Anthony J., Beno, David W. A., Zhang, Xiaolin, Shapiro, Robin, Mason, Mark, Mason-Bright, Tanita, Surber, Bruce, Edens, Neilé K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412734/
https://www.ncbi.nlm.nih.gov/pubmed/25618754
http://dx.doi.org/10.1007/s00726-015-1920-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412734/
https://www.ncbi.nlm.nih.gov/pubmed/25618754
http://dx.doi.org/10.1007/s00726-015-1920-6

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