A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology

Bone morphogenetic proteins (BMPs), members of the TGF-β superfamily, have numerous biological activities including control of growth, differentiation, and vascular development. Using an in vitro co-culture endothelial cord formation assay, we investigated the role of a BMP7 variant (BMP7v) in VEGF,...

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Detalles Bibliográficos
Autores principales: Tate, Courtney M., Mc Entire, Jacquelyn, Pallini, Roberto, Vakana, Eliza, Wyss, Lisa, Blosser, Wayne, Ricci-Vitiani, Lucia, D’Alessandris, Quintino Giorgio, Morgante, Liliana, Giannetti, Stefano, Maria Larocca, Luigi, Todaro, Matilde, Benfante, Antonina, Colorito, Maria Luisa, Stassi, Giorgio, De Maria, Ruggero, Rowlinson, Scott, Stancato, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412825/
https://www.ncbi.nlm.nih.gov/pubmed/25919028
http://dx.doi.org/10.1371/journal.pone.0125697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412825/
https://www.ncbi.nlm.nih.gov/pubmed/25919028
http://dx.doi.org/10.1371/journal.pone.0125697

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