The Evolutionary History of Lethal Metastatic Prostate Cancer

Cancers emerge from an on-going Darwinian evolutionary process, often leading to multiple competing subclones within a single primary tumour(1-4). This evolutionary process culminates in the formation of metastases, which is the cause of 90% of cancer-related deaths(5). However, despite its clinical...

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Detalles Bibliográficos
Autores principales: Gundem, Gunes, Van Loo, Peter, Kremeyer, Barbara, Alexandrov, Ludmil B., Tubio, Jose M.C., Papaemmanuil, Elli, Brewer, Daniel S., Kallio, Heini M.L., Högnäs, Gunilla, Annala, Matti, Kivinummi, Kati, Goody, Victoria, Latimer, Calli, O’Meara, Sarah, Dawson, Kevin J., Isaacs, William, Emmert-Buck, Michael R, Nykter, Matti, Foster, Christopher, Kote-Jarai, Zsofia, Easton, Douglas, Whitaker, Hayley C., Neal, David E., Cooper, Colin S., Eeles, Rosalind A., Visakorpi, Tapio, Campbell, Peter J., McDermott, Ultan, Wedge, David C., Bova, G. Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413032/
https://www.ncbi.nlm.nih.gov/pubmed/25830880
http://dx.doi.org/10.1038/nature14347

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