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Synthesis and Bioactivity of Luffarin I

The first synthesis of Luffarin I, sesterterpenolide isolated from sponge Luffariella geometrica, has been accomplished from commercially available sclareol. The key strategy involved in this synthesis is the diastereoselective reduction of an intermediate ketone. Luffarin I against human solid tumo...

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Detalles Bibliográficos
Autores principales:	Urosa, Aitor, Marcos, Isidro S., Díez, David, Lithgow, Anna, Plata, Gabriela B., Padrón, José M., Basabe, Pilar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413218/ https://www.ncbi.nlm.nih.gov/pubmed/25903281 http://dx.doi.org/10.3390/md13042407

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