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The pediatric template of brain perfusion
Magnetic resonance imaging (MRI) captures the dynamics of brain development with multiple modalities that quantify both structure and function. These measurements may yield valuable insights into the neural patterns that mark healthy maturation or that identify early risk for psychiatric disorder. T...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413243/ https://www.ncbi.nlm.nih.gov/pubmed/25977810 http://dx.doi.org/10.1038/sdata.2015.3 |
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author | Avants, Brian B Duda, Jeffrey T Kilroy, Emily Krasileva, Kate Jann, Kay Kandel, Benjamin T Tustison, Nicholas J Yan, Lirong Jog, Mayank Smith, Robert Wang, Yi Dapretto, Mirella Wang, Danny J J |
author_facet | Avants, Brian B Duda, Jeffrey T Kilroy, Emily Krasileva, Kate Jann, Kay Kandel, Benjamin T Tustison, Nicholas J Yan, Lirong Jog, Mayank Smith, Robert Wang, Yi Dapretto, Mirella Wang, Danny J J |
author_sort | Avants, Brian B |
collection | PubMed |
description | Magnetic resonance imaging (MRI) captures the dynamics of brain development with multiple modalities that quantify both structure and function. These measurements may yield valuable insights into the neural patterns that mark healthy maturation or that identify early risk for psychiatric disorder. The Pediatric Template of Brain Perfusion (PTBP) is a free and public neuroimaging resource that will help accelerate the understanding of childhood brain development as seen through the lens of multiple modality neuroimaging and in relation to cognitive and environmental factors. The PTBP uses cross-sectional and longitudinal MRI to quantify cortex, white matter, resting state functional connectivity and brain perfusion, as measured by Arterial Spin Labeling (ASL), in 120 children 7–18 years of age. We describe the PTBP and show, as a demonstration of validity, that global summary measurements capture the trajectories that demarcate critical turning points in brain maturation. This novel resource will allow a more detailed understanding of the network-level, structural and functional landmarks that are obtained during normal adolescent brain development. |
format | Online Article Text |
id | pubmed-4413243 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-44132432015-05-14 The pediatric template of brain perfusion Avants, Brian B Duda, Jeffrey T Kilroy, Emily Krasileva, Kate Jann, Kay Kandel, Benjamin T Tustison, Nicholas J Yan, Lirong Jog, Mayank Smith, Robert Wang, Yi Dapretto, Mirella Wang, Danny J J Sci Data Data Descriptor Magnetic resonance imaging (MRI) captures the dynamics of brain development with multiple modalities that quantify both structure and function. These measurements may yield valuable insights into the neural patterns that mark healthy maturation or that identify early risk for psychiatric disorder. The Pediatric Template of Brain Perfusion (PTBP) is a free and public neuroimaging resource that will help accelerate the understanding of childhood brain development as seen through the lens of multiple modality neuroimaging and in relation to cognitive and environmental factors. The PTBP uses cross-sectional and longitudinal MRI to quantify cortex, white matter, resting state functional connectivity and brain perfusion, as measured by Arterial Spin Labeling (ASL), in 120 children 7–18 years of age. We describe the PTBP and show, as a demonstration of validity, that global summary measurements capture the trajectories that demarcate critical turning points in brain maturation. This novel resource will allow a more detailed understanding of the network-level, structural and functional landmarks that are obtained during normal adolescent brain development. Nature Publishing Group 2015-02-03 /pmc/articles/PMC4413243/ /pubmed/25977810 http://dx.doi.org/10.1038/sdata.2015.3 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0 Metadata associated with this Data Descriptor is available at http://www.nature.com/sdata/ and is released under the CC0 waiver to maximize reuse. |
spellingShingle | Data Descriptor Avants, Brian B Duda, Jeffrey T Kilroy, Emily Krasileva, Kate Jann, Kay Kandel, Benjamin T Tustison, Nicholas J Yan, Lirong Jog, Mayank Smith, Robert Wang, Yi Dapretto, Mirella Wang, Danny J J The pediatric template of brain perfusion |
title | The pediatric template of brain perfusion |
title_full | The pediatric template of brain perfusion |
title_fullStr | The pediatric template of brain perfusion |
title_full_unstemmed | The pediatric template of brain perfusion |
title_short | The pediatric template of brain perfusion |
title_sort | pediatric template of brain perfusion |
topic | Data Descriptor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413243/ https://www.ncbi.nlm.nih.gov/pubmed/25977810 http://dx.doi.org/10.1038/sdata.2015.3 |
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