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Rifapentine-Proliposomes for Inhalation: In Vitro and In Vivo Toxicity

BACKGROUND: Oral therapy for pulmonary tuberculosis (TB) treatment suffers from the limitation of hepatic metabolism leading insufficient concentration of antitubercular (anti-TB) drugs in alveolar macrophage which harbors Mycobacterium tuberculosis (MTB). Targeted aerosol delivery of antituberculou...

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Detalles Bibliográficos
Autores principales: Patil-Gadhe, Arpana A., Kyadarkunte, Abhay Y., Pereira, Michael, Jejurikar, Gauri, Patole, Milind S., Risbud, Arun, Pokharkar, Varsha B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413410/
https://www.ncbi.nlm.nih.gov/pubmed/25948966
http://dx.doi.org/10.4103/0971-6580.155361