Cargando…
A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells
Dendritic cells (DCs) direct CD4(+) T-cell differentiation into diverse helper (Th) subsets that are required for protection against varied infections. However, the mechanisms used by DCs to promote Th2 responses, which are important both for immunity to helminth infection and in allergic disease, a...
Autores principales: | Cook, Peter C., Owen, Heather, Deaton, Aimée M., Borger, Jessica G., Brown, Sheila L., Clouaire, Thomas, Jones, Gareth-Rhys, Jones, Lucy H., Lundie, Rachel J., Marley, Angela K., Morrison, Vicky L., Phythian-Adams, Alexander T., Wachter, Elisabeth, Webb, Lauren M., Sutherland, Tara E., Thomas, Graham D., Grainger, John R., Selfridge, Jim, McKenzie, Andrew N. J., Allen, Judith E., Fagerholm, Susanna C., Maizels, Rick M., Ivens, Alasdair C., Bird, Adrian, MacDonald, Andrew S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413429/ https://www.ncbi.nlm.nih.gov/pubmed/25908537 http://dx.doi.org/10.1038/ncomms7920 |
Ejemplares similares
-
The Methyl-CpG-Binding Protein Mbd2 Regulates Susceptibility to Experimental Colitis via Control of CD11c(+) Cells and Colonic Epithelium
por: Jones, Gareth-Rhys, et al.
Publicado: (2020) -
Recruitment of MBD1 to target genes requires sequence-specific interaction of the MBD domain with methylated DNA
por: Clouaire, Thomas, et al.
Publicado: (2010) -
Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences
por: Günther, Katharina, et al.
Publicado: (2013) -
A central role for hepatic conventional dendritic cells in supporting Th2 responses during helminth infection
por: Lundie, Rachel J, et al.
Publicado: (2016) -
Modulation of dendritic cell alternative activation and function by the vitamin A metabolite retinoic acid
por: Jones, Lucy H., et al.
Publicado: (2015)