Cargando…

FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic–pituitary–adrenal axis

Fibroblast growth factor-1 (FGF1) and FGF19 have been shown to improve glucose metabolism in diabetic rodents, but how this occurs is unknown. Here to investigate the mechanism of action of these growth factors, we perform intracerebroventricular (ICV) injections of recombinant FGF1 or FGF19 in an a...

Descripción completa

Detalles Bibliográficos
Autores principales: Perry, Rachel J., Lee, Sangwon, Ma, Lie, Zhang, Dongyan, Schlessinger, Joseph, Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413509/
https://www.ncbi.nlm.nih.gov/pubmed/25916467
http://dx.doi.org/10.1038/ncomms7980