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FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic–pituitary–adrenal axis
Fibroblast growth factor-1 (FGF1) and FGF19 have been shown to improve glucose metabolism in diabetic rodents, but how this occurs is unknown. Here to investigate the mechanism of action of these growth factors, we perform intracerebroventricular (ICV) injections of recombinant FGF1 or FGF19 in an a...
Autores principales: | Perry, Rachel J., Lee, Sangwon, Ma, Lie, Zhang, Dongyan, Schlessinger, Joseph, Shulman, Gerald I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413509/ https://www.ncbi.nlm.nih.gov/pubmed/25916467 http://dx.doi.org/10.1038/ncomms7980 |
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