Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/β-catenin pathway

Here we found that levels of cathelicidin, an antimicrobial peptide, were increased in colon cancer tissues compared to noncancerous tissues. Importantly, cathelicidin was mainly expressed in immune cells. Contact with tumor cells caused macrophages to secrete cathelicidin. Neutralization of catheli...

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Detalles Bibliográficos
Autores principales: Li, Dong, Liu, Wenfang, Wang, Xuan, Wu, Junlu, Quan, Wenqiang, Yao, Yiwen, Bals, Robert, Ji, Shurong, Wu, Kaiyin, Guo, Jia, Wan, Haiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413629/
https://www.ncbi.nlm.nih.gov/pubmed/25596747

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