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Paracrine SDF-1α signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells

Pancreatic cancer exhibits the poorest prognosis among all tumors and is characterized by high resistance to the currently available chemotherapeutic agents. Our previous studies have suggested that stromal components could promote the chemoresistance of pancreatic cancer cells (PCCs). Here, we expl...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Wu, Huanwen, Guan, Jian, Wang, Li, Ren, Xinyu, Shi, Xiaohua, Liang, Zhiyong, Liu, Tonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413639/
https://www.ncbi.nlm.nih.gov/pubmed/25609203

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